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COSMETICS SAFETY SERVICES
REGULATORY TOXICOLOGY SERVICES
According to the requirements of the cosmetic regulation (EC) 1223/2009, all cosmetic products prior being placed on the EU market must have a detailed safety assessment known as the Cosmetic Product Safety Report (CPSR).
For the safety assessment, all the necessary data regarding the cosmetic product safety information must be collected and integrated across toxicity endpoints according to the SCCS notes of guidance for the testing and safety evaluation of cosmetic ingredients.
These data could be extracted from both existing database and published data sources generated from in vivo, in vitro testing and in silico prediction. Moreover, it is reported that in silico approaches and in silico data are increasingly important in toxicology for cosmetics as animal testing bans increase.
IBS develops and provides optimized solutions for your cosmetic ingredient, product safety assessment.
TOXICOLOGICAL PROFILE
Toxicological profiles of Cosmetic Ingredients and Raw materials
Toxicological profiles of your cosmetic ingredients and products (synthetic or natural origin) from the simplest to the most innovative method by our integrated solutions of in vivo, in vitro and in silico approaches.
Submit your service inquiry for your safety risk assessment report.
CPSR
Cosmetic Product Safety Report (CPSR) for Formulation/Finished products
Safety information and safety assessment of your Cosmetic ingredients and products (synthetic or natural origin) by our innovated and optimized CPSR reporting process to get cost-effective service and by our in silico toxicology prediction models to fill data gaps.
Submit your service inquiry for your Cosmetic Product Safety Report (CPSR).
IN SILICO SERVICES
Discover the most advanced offer in toxicological end points prediction based on our innovated integrated in silico models, OECD TG 497 and SCCS 11 th guidelines approved tools and using our cosmetic ingredient toxicological database.
The REACH regulation 1907/2006 / EC and Notes of Guidance of the SCCS recommend the use of in silico approach for the evaluation of ingredients and cosmetic products.
Our integrated solutions using in silico prediction models (ISPM) are rapid, cost-effective and according to 3R (Reduce, Refinement and Replacement) strategy of alternative to animal testing.
IBS IN SILICO PREDICTION MODEL
In silico prediction of toxicity profiles consists in prediction of skin permeability, prediction of skin irritation, prediction of skin sensitization.
Submit your inquiry for in silico toxicity prediction of your Cosmetic ingredient and product.
IBS in silico services include:
- QSAR services
- Read across services
- PBPK services
- Skin Permeability prediction
- Skin Irritation/Corrosion prediction
- Skin Sensitization prediction
- Skin Metabolism prediction
- Acute Oral Toxicity
- Estrogen receptor binding
- Targeted Skin proteins binding prediction by Molecular Docking
IN VITRO TESTING PLATFORM
Discover our in vitro testing platform which performs in vitro toxicity assay services and provides tissue and cell based in vitro models. In vitro toxicology testing is largely used by the cosmetic and chemical industries to test the safety and efficacy of cosmetic ingredients and products.
This in vitro approach offers an effective alternative to animal testing and also supports in silico prediction data.
IN VITRO TESTING PLATFORM
Skin Penetration (OECD 428)
Skin Irritation (OECD 439)
Skin Sensitization, KeratinoSens™ (OECD 442D)
IN VITRO MODELS
Skin cells and tissues
Blood cells
Need more info on regulatory in vitro toxicity testing of your ingredient and product?
Or for human tissue-based in vitro models and culture media?
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